Dry mist disinfection

Healthcare-associated infections are one of the most pressing health problems. Recently, there has been an increase in the resistance of bacterial strains to disinfectants, which requires new approaches to infectious safety in medical institutions. To increase the effectiveness of the available methods of disinfection in sites of infection, as well as the prevention of nosocomial infection, a method of aerosol fine disinfection is proposed.

Significant advances in modern medicine in the field of diagnosis and treatment of human diseases, including those that were previously considered incurable, led to an increase in the survival rate of patients, but at the same time created certain problems associated with intrahospital (hospital, nosocomial) infections (HAI), which in the modern period acquire increasing medical and socio-economic importance. They are characterized by a severe clinical progression, the ability to complicate the underlying disease and high mortality, which, according to some authors, ranges from 14% to 58.6% in various nosological forms, and in some cases up to 82.2%. According to the WHO, the mortality rate in patients with nosocomial infections is 10 times higher than that in patients without this infection. Outbreaks of nosocomial infections are also a significant problem.

The greatest risk of nosocomial infections exists in intensive care units, surgical, urological, burns, trauma departments, that is, where patients with a lesion or deficiency of the immune defense system are concentrated, who experience a significant number of invasive interventions.

The economic losses from these infections are estimated in hundreds of thousands dollars and consist of direct and additional costs associated with an increase in the length of stay of patients in the hospital, an increase in the cost of laboratory tests, and the treatment of patients. It is impossible to deny the moral damage from the "additional" infection, which can lead to disability and even death of the patient.

Special sample studies carried out in medical institutions of various profiles show that the true number of nosocomial infections is 50 - 100 times higher than the officially registered one.

In the conditions of domestic hospitals, organizational, sanitary-hygienic and sanitary-technical problems can also contribute to the spread of nosocomial infections, in particular:

• violation of the rules for the preparation of working solutions
• violation of the schedules and regime of cleaning and disinfection of wards
• failure in the operation of supply and exhaust ventilation and air conditioning systems
• human factor

Currently, routine cleaning and disinfection is performed by a human operator using liquid detergents or disinfectants. Microbiological studies show that routine cleaning and disinfection without targeted improvement rarely removes pathogens from surfaces [39], [40], [41], [42]. For example, MRSA was identified on 66% of the surface in wards after final cleaning in one study [39], and C. difficile spores persisted despite disinfection with bleaching in another study [43], [44], [45]

Traditional spraying and wiping can get rid of some germs. But manual disinfection is as effective as cleaning carried out by a person. In contrast, the Dr. Fogg dry mist disinfection System (so-called aerosol generator) eliminates the effects of the human factor through an automatic dry mist disinfection process that reaches every surface in the room, ensuring complete disinfection of the room. The system includes aerosolized hydrogen peroxide that kills up to 99% of microorganisms.

Principle of operation

The principle of the method is based on the transformation of a liquid disinfectant into a state of a finely dispersed aerosol, which fills the entire volume of the room, which disinfects the surfaces of objects in hard-to-reach and remote places (walls, floor, equipment, furniture).

• The aerosol generator converts a liquid disinfectant solution into particles up to 20 microns in size, which disinfect the air and room surfaces
• Drops up to 20 microns are classified as dry mist. These particles have a good diffusion effect, they are evenly distributed throughout the room, penetrating into hard-to-reach and remote places.
• The time of disinfection of the room depends on its volume and the calculated concentration of H2O2

A high level of safety, cost-effectiveness and environmental friendliness, lack of sensitization of the body and risk for personnel allow us to recommend the method of aerosol disinfection as a progressive one.

This method of disinfection is recommended by order of the Ministry of Health of Ukraine No. 236.

The disinfection cycle consists of three stages:

• Spraying is calculated automatically depending on the volume of the room
• Exposure of a given concentration for the effect of a disinfectant on microorganisms
• Disinfectant decomposition into water and oxygen

Method of application: For disinfection of premises by aerosol spraying, a concentration of 3 ml / m3 of disinfectant is recommended

Disinfectant consumption:

Room volume	Consumption
30 m3	90 ml
60 m3	180 ml
90 m3	270 ml

 

References:

39. French G.L., Otter J.A., Shannon K.P., Adams N.M., Watling D., Parks M.J. Tackling contamination of the hospital environment by methicillin-resistant Staphylococcus aureus (MRSA): a comparison between conventional terminal cleaning and hydrogen peroxide vapour decontamination. J Hosp Infect. 2004;57:31–37. [PubMed] [Google Scholar]
40. Byers K.E., Durbin L.J., Simonton B.M., Anglim A.M., Adal K.A., Farr B.M. Disinfection of hospital rooms contaminated with vancomycin-resistant Enterococcus faecium. Infect Control Hosp Epidemiol. 1998;19:261–264. [PubMed] [Google Scholar]
41. Manian F.A., Griesenauer S., Senkel D. Isolation of Acinetobacter baumannii complex and methicillin-resistant Staphylococcus aureus from hospital rooms following terminal cleaning and disinfection: can we do better? Infect Control Hosp Epidemiol. 2011;32:667–672. [PubMed] [Google Scholar]
42. Wilcox M.H., Fawley W.N., Wigglesworth N., Parnell P., Verity P., Freeman J. Comparison of the effect of detergent versus hypochlorite cleaning on environmental contamination and incidence of Clostridium difficile infection. J Hosp Infect. 2003;54:109–114. [PubMed] [Google Scholar]
43. Boyce J.M., Havill N.L., Otter J.A. Impact of hydrogen peroxide vapor room decontamination on Clostridium difficile environmental contamination and transmission in a healthcare setting. Infect Control Hosp Epidemiol. 2008;29:723–729. [PubMed] [Google Scholar]
44. Verity P., Wilcox M.H., Fawley W., Parnell P. Prospective evaluation of environmental contamination by Clostridium difficile in isolation side rooms. J Hosp Infect. 2001;49:204–209. [PubMed] [Google Scholar]
45. Kaatz G.W., Gitlin S.D., Schaberg D.R. Acquisition of Clostridium difficile from the hospital environment. Am J Epidemiol. 1988;127:1289–1294. [PubMed] [Google Scholar]